UN Number: 2280 - CAS Number: 124-09-4

Also known as: 1,6-Hexanediamine, 1,6-Diaminohexane, Hexane-1,6-Diamine, Hmda, Hexamethylenediamine
Information on chemical

Information on chemical

External resources

CAMEO Chemical Database
WISER Substance List


UN number 2280
CAS number 124-09-4
Formula C6H16N2

Physical chemical data

Physical State (25°C) Solid
Molar mass (g/mol) 116.204
Solubility (g/L)
10000000 [g/L] at a temperature of 20°C and salinity of 0‰
Boiling Point (°C) 204.6
Melting Point (°C) 39.13
Flash Point (Cleveland open cup) (°C) 71
Lower explosivity limit (LEL) (volume %) 0.7
Upper explosivity limit (UEL) (volume %) 6.3
Combus enthalpy (J/Kg) 28400000
Henry's constant (mol/(m³·Pa)) 7e-05

Behaviour at sea

Log kow 0.35
Log koc 2.21
Biodegradation in marine environment (Half-life) (days) Not biodegradable
Bioconcentration factor (BCF) 1

Additional data

MARPOL pollution category
Category Description
Y Noxious Liquid Substances which, if discharged into the sea from tank cleaning or deballasting operations, are deemed to present a hazard to either marine resources or human health or cause harm to amenities or other legitimate uses of the sea and therefore justify a limitation on the quality and quantity of the discharge into the marine environment.

Transportation data

Reactivity data

Abilities Soluble in water.

GESAMP Hazard profile

Bioaccumulation in logPow (A1A) 0 - e <1, or > ca.7, or Mol. Wt. > 1000
Bioaccumulation (A1) 0 - No potential to bioaccumulate
Biodegradation (A2) R - Readily biodegradable
Acute aquatic toxicity (B1) (LC/EC/IC50 (mg/l)) 2 - Slightly toxic
Acute mammalian toxicity by swallowing (C1) (LD50 (mg/kg)) 1 - Slight
Acute mammalian toxicity by skin penetration (C2) (LD50 (mg/kg)) 0 - Negligible
Acute mammalian toxicity by inhalation (C3) (LC50 (mg/l)) 2 - Moderate
Skin irritation/corrosivity (D1) 1 - Mildly irritating
Eye irritation/corrosivity (D2) 1 - Mildly irritating
Interference with coastal amenities (E2) ED - Evaporator/Dissolver
Effects on wildlife and bottom habitats (E3) 3 - Is highly acutely toxic; and/or is severely irritant or corrosive to skin or eyes; and/or is carcinogenic, mutagenic or reprotoxic; and/or is a floater or persistent floater with associated health effects

Human toxicity threshold

Corrosive Harmful
Hazard statements
H302 Harmful if swallowed.
H312 Harmful in contact with skin.
H314 Causes severe skin burns and eye damage.
H335 May cause respiratory irritation.
Precautionary statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301 + P330 + P331 IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
P303 + P361 + P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/physician.


Lowest median lethal concentration (LC50) on algae (mg/l) 14.8
Lowest median lethal concentration (LC50) on crustacean (mg/l) 23.4
Lowest median lethal concentration (LC50) on fishes (mg/l) 73.5
Highest no observed effect concentration (NOEC) on algae (mg/l) 3.2
Highest no observed effect concentration (NOEC) on crustacean (mg/l) 4.16
Assessment factor (AF)
100 on the Short term
Predicted No Effect Concentration (PNEC) (µg/l)
40 [µg/l] on the Short term
Incident reports

Incident reports

No incident reports available

Emergency Response Guidebook

Emergency Response Guidebook

Guide number: 153

See the guide or download the emergency response guidebook

At sea emergency guide

At sea emergency guide

No guides available

Decision trees

Decision trees

No decision trees available

No additional data

last modified 2023-01-23T14:29:19+00:00

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